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Cancer - good news of a cure at last

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Comments

  • #102
    endacl
    Registered Users, Registered Users 2 Posts: 22,412 ✭✭✭✭endacl


    Junkyard Tom wrote: »
    Not my alternative but one that might work.

    https://en.wikipedia.org/wiki/Prizes_as_an_alternative_to_patents#The_Medical_Innovation_Prize_Fund_Act_S1137_and_S1138
    Interesting all right. I'd come across that before. It deals with generics though. What were talking about here is a radically new therapy. Not a generic.


  • #103
    endacl
    Registered Users, Registered Users 2 Posts: 22,412 ✭✭✭✭endacl


    sullivlo wrote: »
    Some of my work was published in popular science world (as a pose to peer reviewed science world). It was published in laymans terms in order to try to convey what we were doing, why we were doing it, and what kind of results we were getting. I regularly (at the time, less so now) would get emails from terminally ill cancer patients who had heard of the drug we were working with, and asking how the could access it. It was heartbreaking to see people get their hopes up and think "woo hoo, this kills cancer" to only realise that no, it's too late for me. I saw it towards the end of my aunts illness - she clung on to every bit of hope.

    Mainstream media have a lot to answer for in terms of how they present their headlines.

    "Cure for 94% of cancer patients" grabs attention, but fails to mention that it's only one sub type of one type of cancer that has been treated. This would have no impact on anyone with a different form of cancer.

    Indeed. And it's a lot easier to deliver the therapeutic payload to a blood borne cancer. The affected area being the means of transmission of the remedy. It'll be interesting to see results from trials delivering modified CAR-T cells to lungs and liver etc.


  • #104
    kleefarr
    Registered Users, Registered Users 2 Posts: 5,744 ✭✭✭kleefarr


    murpho999 wrote: »
    Why are people already having a go at pharmaceutical companies for making money out of their products.

    That's the way the world works.

    If it really worked it would just eventually replace contemporary less effective treatments.
    Also, research into these drugs costs billions but that doesn't get mentioned.

    If these companies could not make profits then we would have a lot less medical advances that we have seen over the last 100 years.

    Agreed. It's not always so simple though.
    When in Oregon USA last year I noticed that they freely advertise pharmaceutical drugs on TV.
    At the end of the advert there was always a big list of 'possible' side effects.

    Made me think.


  • #105
    sullivlo
    Registered Users, Registered Users 2 Posts: 9,994 ✭✭✭sullivlo


    endacl wrote: »
    Indeed. And it's a lot easier to deliver the therapeutic payload to a blood borne cancer. The affected area being the means of transmission of the remedy. It'll be interesting to see results from trials delivering modified CAR-T cells to lungs and liver etc.

    Oddly, our compound is inactived by blood, so only works on epithelial cancers without blood circulating - skin, bladder, colon.

    The trials on the solid tumours with the immuno technique will be fascinating. We're collaborating on immuno-cancer therapeutics at the moment and figuring out how they work and why they work. It is an incredible field. So interesting. It really needed some sort of explosion to kick it off. Hopefully this will be it!

    It's just such a novel approach. I love it.


  • #106
    sullivlo
    Registered Users, Registered Users 2 Posts: 9,994 ✭✭✭sullivlo


    kleefarr wrote: »
    Agreed. It's not always so simple though.
    When in Oregon USA last year I noticed that they freely advertise pharmaceutical drugs on TV.
    At the end of the advert there was always a big list of 'possible' side effects.

    Made me think.

    The advertising isn't legal here. It's done through doctors instead. Freebies offered in exchange for prescribing the new drug. Once the patents expire they don't make money on the branded drugs.

    And side effects have to be listed. Some would be well known and documented. Others are anomalies and coincidental occur - "frequency unknown".

    Then of course is the unintentional side effects that become drugs themselves. Such as viagra!


  • #107
    zl1whqvjs75cdy
    Closed Accounts Posts: 4,042 ✭✭✭zl1whqvjs75cdy


    sullivlo wrote: »
    The advertising isn't legal here. It's done through doctors instead. Freebies offered in exchange for prescribing the new drug. Once the patents expire they don't make money on the branded drugs.

    And side effects have to be listed. Some would be well known and documented. Others are anomalies and coincidental occur - "frequency unknown".

    Then of course is the unintentional side effects that become drugs themselves. Such as viagra!

    The freebies are also now illegal.


  • #108
    Junkyard Tom
    Registered Users, Registered Users 2 Posts: 10,117 ✭✭✭✭Junkyard Tom


    endacl wrote: »
    Interesting all right. I'd come across that before. It deals with generics though. What were talking about here is a radically new therapy. Not a generic.

    Disney say anything about restricting research to generics only. Actually generics don't require research - generics require duplication.
    There is an alternative way of financing and incentivizing research that, at least in some instances, could do a far better job than patents, both in directing innovation and ensuring that the benefits of that knowledge are enjoyed as widely as possible: a medical prize fund that would reward those who discover cures and vaccines

    www.paecon.net/pdf


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