[Diabetes] Compounding pharmacy that will dilute insulin

joaomajesus

Hi,

Does anyone know of a compounding pharmacy that will dilute insulin, preferably in the Dublin area?

Thanks!

locum-motion

As a pharmacist, I cannot think of any reason why one would want to dilute insulin, nor have I ever heard of a pharmacy that would have the facilities to do so.

(If a small dose is needed, a small volume is used, rather than diluting it.)

The Hound Gone Wild

There's a Pharmacy near the Eye & Ear hospital in Dublin with an aseptic room for extemp eye drops. They would be the only community pharmacy I know of with the facilities to attempt this. I doubt any Pharmacist would actually do it. I wouldn't

If you are running low on insulin go to a Pharmacy with your insulin and see if you can get an emergency supply. If you haven't gotten an LTI number yet you'll have to pay privately.

gctest50

locum-motion wrote: »

As a pharmacist, I cannot think of any reason why one would want to dilute insulin, nor have I ever heard of a pharmacy that would have the facilities to do so.

(If a small dose is needed, a small volume is used, rather than diluting it.)

It's to give more accuracy at small doses

( low carb intake or maybe for small kids/kittens etc )


The supplier should provide diluent or ask them if saline is ok

locum-motion

gctest50 wrote: »

It's to give more accuracy at small doses

( low carb intake or maybe for small kids/kittens etc )


The supplier should provide diluent or ask them if saline is ok

How small a dose are you talking about?

gctest50

½ unit of insulin may drop a 2yr old by 8 mmol

gctest50

.

This case series describes three young children between 1 and 4 years of age treated by insulin pump.

.......all three had suboptimal blood glucose control (mean HbA1c, 8.1%).

After switching to diluted U10 insulin, HbA1c levels improved at 3 and 9 months (7.3% and 6.7%, respectively).

Moreover, when two of the patients changed back to U100 insulin via pump, HbA1c values deteriorated to 8.5% and 8.7% within 2 months.

joaomajesus

locum-motion wrote: »

As a pharmacist, I cannot think of any reason why one would want to dilute insulin, nor have I ever heard of a pharmacy that would have the facilities to do so.

(If a small dose is needed, a small volume is used, rather than diluting it.)

The reason is to be able to do micro dosing. Atm I'm able to do 1/2 units only and that lowers my blood sugar by 1.4mmol/L. Since my target is 4.6mmol/L I can only do a correction at 6mmol/L. If I do a 1/4 unit then I could do a correction at 5.3mmol/L. This would allow me to do a more fine control.

Btw I'm doing very low carb so I use small doses of insulin.

My A1c is at 33mmol/mol and with finer control I believe I could get to the normal a1c of 22.4-24.8.

joaomajesus

locum-motion wrote: »

How small a dose are you talking about?

In my case I'm looking to get to 1/4 of a unit.

gctest50

A pump will do down to 0.025 units

joaomajesus

gctest50 wrote: »

A pump will do down to 0.025 units

Yes. I know

I'm taking care of the LTI and I'll see if I can get a pump. Although I don't think I qualify because my A1C is too low

joaomajesus

The Hound Gone Wild wrote: »

There's a Pharmacy near the Eye & Ear hospital in Dublin with an aseptic room for extemp eye drops. They would be the only community pharmacy I know of with the facilities to attempt this. I doubt any Pharmacist would actually do it. I wouldn't

If you are running low on insulin go to a Pharmacy with your insulin and see if you can get an emergency supply. If you haven't gotten an LTI number yet you'll have to pay privately.

Cool. Can you tell me which one is it?
Thanks.