COVID-19: Vaccine and testing procedures Megathread Part 2 [Mod Warning - Post #1]

nommm

https://twitter.com/annaholligan/status/1340737145766604808?s=21

Water John

EU price list leaked by Belgian Minister;
This is the list of what the EU is paying:

Oxford/AstraZeneca: €1.78 (£1.61).
Johnson & Johnson: $8.50 (£6.30).
Sanofi/GSK: €7.56.
Pfizer/BioNTech: €12.
CureVac: €10.
Moderna: $18.

stephenjmcd

is_that_so wrote: »

Yeah, I agree on the 1m target. Actually, it's the last four groups that make up the bulk of the population, about 3.5m of them in total.

Depends really what way they end up going. Theres a hell of alot that based on their occupation could be bumped up the list.

never_mind

OH got tested yesterday at 9.30 and still no results.symptoms are gone so prob a cold but still. Thought this was super efficient?

Oxford providing final data to MHRA tomorrow too, I know these things shouldn't be political but given the events in the UK in recent days I wouldn't be too surprised if they try and push approval through by Christmas day.

JacksonHeightsOwn

never_mind wrote: »

OH got tested yesterday at 9.30 and still no results.symptoms are gone so prob a cold but still. Thought this was super efficient?

we waited 2 days for a result for our little lad two weeks ago.toughest 3 days ive had in the house throughout the whole lockdown, he was a rapid dog climbing the walls. Thankfully given the all clear at 9.30 and i dragged him back to the school to let him "run free"

never_mind

chrisbonnie wrote: »

we waited 2 days for a result for our little lad two weeks ago.toughest 3 days ive had in the house throughout the whole lockdown, he was a rapid dog climbing the walls. Thankfully given the all clear at 9.30 and i dragged him back to the school to let him "run free"

You were waiting two or three days? I’m very stressed over it as I’d be a close contact then abd my Xmas might be f’ed..

is_that_so

Water John wrote: »

EU price list leaked by Belgian Minister;
This is the list of what the EU is paying:

Oxford/AstraZeneca: €1.78 (£1.61).
Johnson & Johnson: $8.50 (£6.30).
Sanofi/GSK: €7.56.
Pfizer/BioNTech: €12.
CureVac: €10.
Moderna: $18.

Yeah, these prices have been hinted at for a good while so it was no great shock when she revealed them.

JacksonHeightsOwn

never_mind wrote: »

You were waiting two or three days? I’m very stressed over it as I’d be a close contact then abd my Xmas might be f’ed..

yeah, it annoyed us no end.

We rang the doctor at 8.30 on the Monday morning, didnt get a repky until 4p,, even though we kept ringing back.

The test was 10am Tuesday morning, at 9am Thursday morning we still didnt hear anything back so we rang some helpline, they said just wait, within 30 minutes we got the text saying he was negative.

Friends of ours had their children tested and all got the results back within 2 hours so i was expected one day, like yourself

never_mind

chrisbonnie wrote: »

yeah, it annoyed us no end.

We rang the doctor at 8.30 on the Monday morning, didnt get a repky until 4p,, even though we kept ringing back.

The test was 10am Tuesday morning, at 9am Thursday morning we still didnt hear anything back so we rang some helpline, they said just wait, within 30 minutes we got the text saying he was negative.

Friends of ours had their children tested and all got the results back within 2 hours so i was expected one day, like yourself

We’ll call tomorrow if it’s still radio silence!!! Thanks a mil for that x

braychelsea

Novavax expected to report results January as well. By March there is a strong possibility we could have 5 vaccines. Provided government are capable of ramping up rollout we could have the majority of the population vaccinated by summer.

Doc07

nommm wrote: »

Will the EMA meeting tomorrow be streamed like the FDA meetings?

On JnJ, I think February is the earliest we get it as vaccine needs 2 months of safety data and they only finished enrolling recently.

The scientific committee meeting won’t be steamed live. The EMa will host a press conference at 3 (2 Irish times) ans announce the verdict then.
The FDA didn’t live steak their own internal meeting , it was actually a meeting of their vaccine advisory committee who give their independent expert recommendation to the FDA (who usually come to same conclusion)
The EMA will publish very quickly on their website ,maybe Tuesday or Wednesday a detailed summary of the evidence they assessed and why they approved it (assuming it’s approved tomorrow)
They will also publish the plan for all the close
Monitoring and additional studies to make sure the vaccine remains to have a positive benefit risk it is rolled out.
They have already published a summary of the special studies in children which will be carried out to see if it’s also effective and safe in children.

never_mind

I'm not up to speed on the current state of play for the EU response to the vaccines; but you wouldn't think they push up the date seeing as there is this new variant and looming hard lockdown?

Water John

braychelsea wrote: »

Novavax expected to report results January as well. By March there is a strong possibility we could have 5 vaccines. Provided government are capable of ramping up rollout we could have the majority of the population vaccinated by summer.

I think there were 3 vaccines expected earlier, to be followed by 5 more, a total of 8 in the Spring/Summer.

nommm

never_mind wrote: »

I'm not up to speed on the current state of play for the EU response to the vaccines; but you wouldn't think they push up the date seeing as there is this new variant and looming hard lockdown?

Pfizer will be approved tommorow for EU.

braychelsea

Water John wrote: »

I think there were 3 vaccines expected earlier, to be followed by 5 more, a total of 8 in the Spring/Summer.

Think that might include Chinese and Russian vaccines? I was just referring to vaccines which we have deals with. Great news regardless.

ACitizenErased

nommm wrote: »

https://twitter.com/annaholligan/status/1340737145766604808?s=21

I’ll try find a link for this tomorrow before its on and post it in here

Water John

braychelsea wrote: »

Think that might include Chinese and Russian vaccines? I was just referring to vaccines which we have deals with. Great news regardless.

I don't think so, but accept your possibly correct.

These are six listed previously;
Oxford/AstraZeneca: 1st Gen
Johnson & Johnson: 2nd Gen
Sanofi/GSK: 2nd Gen
Pfizer/BioNTech: 1st Gen
CureVac: 2nd Gen
Moderna: 1st Gen

stephenjmcd

https://twitter.com/AFP/status/1340734983661600769?s=19

ACitizenErased

Not a sign of that in any of the news outlets here. We're being ridden.

Russman

Deleted User wrote: »

Oxford providing final data to MHRA tomorrow too, .

Are they really ? (Not doubting you, just wasn’t aware)
That’s excellent news if they have their final data ready to go. EMA application can’t be far behind.

odyssey06

ACitizenErased wrote: »

Not a sign of that in any of the news outlets here. We're being ridden.

The cavalry (vaccines) are on their way but they aren't here yet... gonna have to circle the wagons a while longer.

ixoy

Would blockades to mainland Europe for shipping have any impact on the manufacture / distribution of the vaccine? For example, according to the Financial Times here, part of the Oxford vaccine is developed in the UK.

JacksonHeightsOwn

Luke O'Neill was just on with pat Kenny and he said the vaccines will definitely still work to the new variant

Also said he'd expect us to have access to 13 million vaccines by quarter 1 of the new year.

Gile_na_gile

chrisbonnie wrote: »

Also said he'd expect us to have access to 13 million vaccines by quarter 1 of the new year.

Like on Saturday, he must be referring to the foreseen authorisation of the Oxford vaccine. Good enough but not excellent efficacy, but there is wide availability. Has to happen regardless. Perhaps when the rest of the world is vaccinated many of us can 'top up' with mRNA vaccines next year if they are compatible.



Still not clear if there will be further information on the HD/FD regime, as authorisation forthcoming is for the FD/FD only, I think.

Russman

Gile_na_gile wrote: »

Like on Saturday, he must be referring to the foreseen authorisation of the Oxford vaccine. Good enough but not excellent efficacy, but there is wide availability. Has to happen regardless. Perhaps when the rest of the world is vaccinated many of us can 'top up' with mRNA vaccines next year if they are compatible.



Still not clear if there will be further information on the HD/FD regime, as authorisation forthcoming is for the FD/FD only, I think.

Is that correct ? I thought I saw an interview a couple of weeks back with Adrian Hill, shortly after the interim results were out, were he said the half dose, full dose would be what they'd be applying for. Open to correction.

CIARAN_BOYLE

Russman wrote: »

Is that correct ? I thought I saw an interview a couple of weeks back with Adrian Hill, shortly after the interim results were out, were he said the half dose, full dose would be what they'd be applying for. Open to correction.

There's definitely an argument to be made that the sample for hd/fd is too small to rule out statistical errors and that its high efficacy numbers could be down to the small sample size and statistical error.

Its something the ema would have to consider before approval.

stephenjmcd

Russman wrote: »

Is that correct ? I thought I saw an interview a couple of weeks back with Adrian Hill, shortly after the interim results were out, were he said the half dose, full dose would be what they'd be applying for. Open to correction.

Would be up to the EMA at the end of the day.

They could apply with both then its a regulatory decision as to if one or both get approved.

Either way the data will be accepted by EMA for review.

Gile_na_gile

Yes, they will probably consider it in the review but will seek more data. I know the MHRA in the UK are getting new data today so perhaps the EMA too. As it happened Luke O'Neill quoted the 62% figure, so was referring to authorisation for FD/FD for which data are robust. There was also the talk of looking at two different vectors in collab with Sputnik V, but that seems to be just a bit of spin as nothing more about that since.

chrisbonnie

chrisbonnie wrote: »

Luke O'Neill was just on with pat Kenny and he said the vaccines will definitely still work to the new variant

Also said he'd expect us to have access to 13 million vaccines by quarter 1 of the new year.

By the end of March? We won't. If we have a few million doses by then we'll have done really well.