COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

gazzer

Realistically when is the estimated timelinevframev for a healthy 49 year old to get the vaccination?

Bubbaclaus

mobby wrote: »

95 year old Mother in law got a Phone call this morning from her GP to inform her that her vaccine date is 5th March, almost 3 weeks away.

So much for over 85's been done this week.

?

Nobody ever even remotely suggested that all over 85s are being done this week.

is_that_so

mobby wrote: »

95 year old Mother in law got a Phone call this morning from her GP to inform her that her vaccine date is 5th March, almost 3 weeks away.

So much for over 85's been done this week.

Only 12,000 doses in 84 GP practices this week - it's a test run. Oh and we are doing another 68,000 second doses elsewhere.

is_that_so

gazzer wrote: »

Realistically when is the estimated timelinevframev for a healthy 49 year old to get the vaccination?

Probably late summer, maybe a bit sooner if they get up to 1m a month. J&J single shots will definitely change dates. 200m ordered by EU so that's about 2m for us. The EMA are expecting an application for approval "within days".

BlueSkys102

mobby wrote: »

95 year old Mother in law got a Phone call this morning from her GP to inform her that her vaccine date is 5th March, almost 3 weeks away.

So much for over 85's been done this week.

I'm wondering will my grandmother be called for this shortly? She is 94 and has left the house once since xmas to walk around the block.

I don't normally voice my opinion about how to Irish government works but I think they are failing the country in not getting this rolled out quicker. Alot of health workers are still waiting on their 1st vaccines

celt262

BlueSkys102 wrote: »

I don't normally voice my opinion about how to Irish government works but I think they are failing the country in not getting this rolled out quicker. Alot of health workers are still waiting on their 1st vaccines

How can this be i know admin people and maintenance people who work in the local hospital and they have all got 2nd jabs.

How many is a lot are is there a source to this?

ixoy

BlueSkys102 wrote: »

I don't normally voice my opinion about how to Irish government works but I think they are failing the country in not getting this rolled out quicker.

They haven't gotten the vaccines to roll them out any faster. They're using what they can - the issue is with the EU supply, which is a different topic.

Water John

Apogee wrote: »

Donnelly hoping to reach 250,000 vaccinations per week. So 1 million+ doses delivered per month and 1 million administered.



https://www.irishtimes.com/news/health/covid-19-donnelly-hoping-to-reach-250-000-vaccinations-a-week-as-programme-ramps-up-1.4485177

That's the magic number, 250K/wk that I was hoping for. That means most will have got their second shot by about the end of July.

funnydoggy

Mother got a phone call today from the GP surgery. They were going through the vaccine stuff, and my granda's name came up as high priority for the shot. He would be second in the third cohort, but they said there are leftover vaccines and he's been cocooning since February last year on his own (recently widowed). They said they'll contact her within the next 2 weeks for his vaccine date.


Poor guy was bawling crying on the phone to my mom when she broke the news. He said he wants her to text immediately with a date because he wants to have his bath, put on nice clothes etc.

I'm so so so so happy. He's been dealing with depression since my nan died 3 years ago, and his lifeline was socialising with his friends in the pub. Of course it isn't possible yet, but he's on the road to it and he's delighted.

Happy days

Theboinkmaster

funnydoggy wrote: »

Mother got a phone call today from the medigroup in Cathedral Road, Cork. They were going through the vaccine stuff, and my granda's name came up as high priority for the shot. He would be second in the third cohort, but they said there are leftover vaccines and he's been cocooning since February last year on his own (recently widowed). They said they'll contact her within the next 2 weeks for his vaccine date.


Poor guy was bawling crying on the phone to my mom when she broke the news. He said he wants her to text immediately with a date because he wants to have his bath, put on nice clothes etc.

I'm so so so so happy. He's been dealing with depression since my nan died 3 years ago, and his lifeline was socialising with his friends in the pub. Of course it isn't possible yet, but he's on the road to it and he's delighted.

Happy days

Nice to hear stories like that, thanks for sharing.

ACitizenErased

EU in talks with Moderna and Astrazeneca for new vaccine deal
https://www.reuters.com/article/us-health-coronavirus-eu-vaccines-idUSKBN2AF1HG?taid=602aa3ebbbd8010001ee61bf&utm_campaign=trueAnthem:+Trending+Content&utm_medium=trueAnthem&utm_source=twitter

funnydoggy

Theboinkmaster wrote: »

Nice to hear stories like that, thanks for sharing.

I didn't expect the end of this shítshow to be so positive, if you get me.

is_that_so

Israel's rate of vaccination has slowed as it moves to the younger groups. The reasons are unclear.

This month, despite jabs being made available to anyone over the age of 16, that figure has often dropped to fewer than 60,000, according to health ministry statistics.

https://www.theguardian.com/world/2021/feb/15/israel-battles-covid-misinformation-vaccination-drive-slows

gazzer

is_that_so wrote: »

Probably late summer, maybe a bit sooner if they get up to 1m a month. J&J single shots will definitely change dates. 200m ordered by EU so that's about 2m for us. The EMA are expecting an application for approval "within days".

Thanks for that.

I'm being selfish. Its my 50th in Sept and I'd love to go out celebrating with about 25)30 mates. I'd love to hire a function room for about 120 but I don't think we will be at that level of easeness then

is_that_so

Here's a list of vaccination centres to date, 37 of them. For most people the process will be by self-registering.

https://www.rte.ie/news/2021/0215/1197176-covid19-vaccines-ireland/

josip

is_that_so wrote: »

Israel's rate of vaccination has slowed as it moves to the younger groups. The reasons are unclear.

https://www.theguardian.com/world/2021/feb/15/israel-battles-covid-misinformation-vaccination-drive-slows

It will happen to all countries at some stage as those eager to be vaccinated have all been done.

It's nothing to do with the younger groups, it just means they're coming to the next stage of the program which will probably be a bit of carrot, in order to try and reach herd immunity.
After that it will be stick.

Serbia will have the same problem even though they're ahead now; they have a very large percentage of vaccine-reluctant.

The UK are more vaccine-eager I think, so they'll get up to at least 60% before it drops off.

cunnifferous

Getting the AZ vaccine on Wednesday. While I'm happy to have some level of protection, I am concerned about it's efficacy and the fact that I could still bring the virus back into my home from work. (38% of people on the two dose regimen still had mild or moderate symptoms meaning that presumably they were infectious) Also my second dose is scheduled for May by which time I would expect the variants that this vaccine appears to ineffectual against to be more prevalent.

Anyway sorry don't want to be a downer on this. I know it's a great relief and source of optimism for many people. Most of the really high risk people are getting the Pfizer vaccine which is more effective, and this is right.

hmmm

cunnifferous wrote: »

Getting the AZ vaccine on Wednesday. While I'm happy to have some level of protection, I am concerned about it's efficacy and the fact that I could still bring the virus back into my home from work. (38% of people on the two dose regimen still had mild or moderate symptoms meaning that presumably they were infectious) Also my second dose is scheduled for May by which time I would expect the variants that this vaccine appears to ineffectual against to be more prevalent.

I saw Gottlieb being interviewed over the weekend. His view was that the more worrisome variants wouldn't become prevalent (if they do at all) until later in the year at which times boosters would be available if required. I think he suggested the vaccine manufacturers would be producing new vaccines around July.

Even leaving that aside, there's (apparently) a lot more to immunity than just antibodies which the new variants are being tested against. There is no evidence so far that any new variant will affect the ability of vaccines to prevent serious disease.

castletownman

is_that_so wrote: »

Here's a list of vaccination centres to date, 37 of them. For most people the process will be by self-registering.

https://www.rte.ie/news/2021/0215/1197176-covid19-vaccines-ireland/

I find it mad that I am equidistant from two vaccine centres no more than twenty minutes away via motorway from me either direction (Arklow and Enniscorthy), yet there are large swathes of geography along the west coast accommodated by only one centre per county.

Thought there'd be an extra one in rural Galway, Mayo and Donegal, and maybe one in South Kerry too.

But it's an exciting development regardless.

Galwayguy35

Deleted User wrote: »

“Hey Boris, will you sell us some of your vaccines”

“Sure, 20% of our population is enough and we really love treating our neighbours well”

Do you believe there are millions off doses just waiting on shelves to be bought. Everyone is using vaccines when the become available

Smart and all as you think you are you are wrong, it was on Sky News last week that they will have way more than is needed for their population.

lbj666

castletownman wrote: »

I find it mad that I am equidistant from two vaccine centres no more than twenty minutes via motorway from me either direction (Arklow and Enniscorthy), yet there are large swathes of geography along the west coast accommodated by only one centre per county.

Thought there'd be an extra one in rural Galway, Mayo and Donegal, and maybe one in South Kerry too.

But it's an exciting development regardless.

Population density comes into and don't forget that GP Clinics Pharmacy's and their facilities will still have a huge role. Especially in those gaps mentioned away from MVCs.

Something that seems totally lost on some of our beloved intellects on journal.ie and Twitter today.

ACitizenErased

Galwayguy35 wrote: »

Smart and all as you think you are you are wrong, it was on Sky News last week that they will have way more than is needed for their population.

By the time they have excess we'll likely be done vaccinating. They're hardly just sitting in a warehouse.

Turtwig

Galwayguy35 wrote: »

Smart and all as you think you are you are wrong, it was on Sky News last week that they will have way more than is needed for their population.

Every first world country will have way more than they need for their population. It doesn't mean excess supplies will be available to other countries right away.

Galwayguy35

ACitizenErased wrote: »

By the time they have excess we'll likely be done vaccinating. They're hardly just sitting in a warehouse.

Turtwig wrote: »

Every first world country will have way more than they need for their population. It doesn't mean excess supplies will be available to other countries right away.

No but its no harm to have the option of getting it off them if needed.

ACitizenErased

Galwayguy35 wrote: »

No but its no harm to have the option of getting it off them if needed.

But there is a 99% chance we won't. The EU have ordered many multiples of our population in vaccines.

JTMan

ACitizenErased wrote: »

EU in talks with Moderna and Astrazeneca for new vaccine deal
https://www.reuters.com/article/us-health-coronavirus-eu-vaccines-idUSKBN2AF1HG?taid=602aa3ebbbd8010001ee61bf&utm_campaign=trueAnthem:+Trending+Content&utm_medium=trueAnthem&utm_source=twitter

Great news. Welcome news including:
- EU would secure 150 million additional doses from Moderna, on top of 160 million that have already been booked.
- Doses under the new deal could be delivered by June.
- Moderna also holding discussions with regulatory authorities in different countries on the possibility of increasing the number of doses in vials to 15 from 10.
- EU is also close to finalising talks with Novavax for 200 million doses.

Plausible that everyone aged 16+ will get a vaccine if they want one by July rather than September.

Water John

castletownman wrote: »

I find it mad that I am equidistant from two vaccine centres no more than twenty minutes away via motorway from me either direction (Arklow and Enniscorthy), yet there are large swathes of geography along the west coast accommodated by only one centre per county.

Thought there'd be an extra one in rural Galway, Mayo and Donegal, and maybe one in South Kerry too.

But it's an exciting development regardless.

The one in your county may not be the nearest to you. South Kerry can go down to Bantry. Most rural people are used to having to travel for services. We're used to it.

cunnifferous

hmmm wrote: »

I saw Gottlieb being interviewed over the weekend. His view was that the more worrisome variants wouldn't become prevalent (if they do at all) until later in the year at which times boosters would be available if required. I think he suggested the vaccine manufacturers would be producing new vaccines around July.



Even leaving that aside, there's (apparently) a lot more to immunity than just antibodies which the new variants are being tested against. There is no evidence so far that any new variant will affect the ability of vaccines to prevent serious disease.

I'm extrapolating from previous variants for which the timeframe for them being detected to becoming significantly prevalent was 2-3 months. The UK variant (B.1.1.7) was identified at it's earliest in samples from September. By December it was the most dominant variant across England. So my timeframe seems reasonable. Most estimates have new versions of vaccines being available in 6+ months. So there are going to be gaps.

There is more to immunity than neutralising antibodies. The T cell response is also key. However the initial evidence for the AZ vaccine in terms of its efficacy against new variants is poor, especially variants containing the E484K mutation. The study is South Africa had a very small sample number but actually measured the amount of people getting mild/moderate Covid symptoms in people who had been AZ vaccinated (which would be a function of their antibody mediated immunity + their T cell mediated immunity) and the results were not promising.

Lastly, yes it may yet still prevent serious illness in people infected with novel variants however as I mentioned earlier my current concern is bringing the virus into my home. At the levels of efficacy it's currently at, which will be reduced by novel variants, I don't see it being very effective at doing that.

Le Bruise

castletownman wrote: »

I find it mad that I am equidistant from two vaccine centres no more than twenty minutes away via motorway from me either direction (Arklow and Enniscorthy), yet there are large swathes of geography along the west coast accommodated by only one centre per county.

Thought there'd be an extra one in rural Galway, Mayo and Donegal, and maybe one in South Kerry too.

But it's an exciting development regardless.

Same for me. 20 minutes to either Greystones or Arklow. Yet there isn’t one in Drogheda (as far as I know)?

hmmm

cunnifferous wrote: »

Lastly, yes it may yet still prevent serious illness in people infected with novel variants however as I mentioned earlier my current concern is bringing the virus into my home. At the levels of efficacy it's currently at, which will be reduced by novel variants, I don't see it being very effective at doing that.

Agreed with that, however I don't think any of the vaccines are being sold with a promise of reducing transmission - the primary endpoints in all the studies was whether they prevented disease. The results from Israel look good from Pfizer, but I personally won't be getting any vaccine with an expectation that it will prevent me from transmitting the virus.

The South African study was so under-powered I'm having difficulty lending it any credibility.