COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

afatbollix

ACitizenErased wrote: »

I'd like to see efficacy after the 42 day threshold that the trials followed. I'm not sure if the UK are collecting data on that?

They can't as nearly everyone has had only one dose

I'd look at the data from Isreal for that kind of results.

afatbollix

afatbollix wrote: »

They can't as nearly everyone has had only one dose

That's exactly the reason why they can do that, not many have been given a second dose so they will be able to test efficacy of single dose up to 12 weeks. They are monitoring it and so far so good.

User142

Squeaksoutloud wrote: »

Just heard Gerry Killeen on The Last Word stating vaccines are not effective against variants. No valid proof except rumblings about Manaus. How can they come on and state this unchallenged when no sufficient evidence to back that opinion and manufacturers stating the opposite. I was in shock at into be honest.

I am the opposite of surprised to see the first post in his twitter feed @'s the zero covid lunatics at 'Independent Scientific Advocacy Group'. The home of complete doom mongering in order to scare the public into believing either their way or all hope is lost.

AdamD

Given the results from the UK should we be clearing AZ for use on our over 65s?

Not approving it at first may well have reduced confidence in taking it within that age group

Gael23

My 83 year old grandparents are getting it on March 2nd

ACitizenErased

Gael23 wrote: »

My 83 year old grandparents are getting it on March 2nd

Thats fantastic to hear under 85s beginning to get it

Turtwig

AdamD wrote: »

Given the results from the UK should we be clearing AZ for use on our over 65s?

Not approving it at first may well have reduced confidence in taking it within that age group

Don't think there's enough data yet to fully support this swing. NIAC will undoubtedly review their assessment as more and more data pours in.

eagle eye

AdamD wrote:

Given the results from the UK should we be clearing AZ for use on our over 65s?
Not approving it at first may well have reduced confidence in taking it within that age group

I was all AZ for a long time, stupid me.
I'm now against it, it being a traditional style vaccine.
Fact is we are still learning about this virus and we don't know enough yet so injecting even a tiny dose into people is a bad idea imo.
The mRNA vaccines are much safer for now.

Turtwig

eagle eye wrote: »

I was all AZ for a long time, stupid me.
I'm now against it, it being a traditional style vaccine.
Fact is we are still learning about this virus and we don't know enough yet so injecting even a tiny dose into people is a bad idea imo.
The mRNA vaccines are much safer for now.

This makes absolutely no sense. Are you saying if you were offered the AZ vaccine you'd refuse it now?

Not sure what you mean by injecting people is a bad either.Anyone taking AZ is a bad idea?

lbj666

eagle eye wrote: »

I was all AZ for a long time, stupid me.
I'm now against it, it being a traditional style vaccine.
Fact is we are still learning about this virus and we don't know enough yet so injecting even a tiny dose into people is a bad idea imo.
The mRNA vaccines are much safer for now.

It's a benign part of the virus to stimulate an immune response that is very very certain, your concern is totally unfounded

ACitizenErased

eagle eye wrote: »

I was all AZ for a long time, stupid me.
I'm now against it, it being a traditional style vaccine.
Fact is we are still learning about this virus and we don't know enough yet so injecting even a tiny dose into people is a bad idea imo.
The mRNA vaccines are much safer for now.

That is just not how the AZ vaccine works. Not even close.

AngeloArgue

eagle eye wrote: »

I was all AZ for a long time, stupid me.
I'm now against it, it being a traditional style vaccine.
Fact is we are still learning about this virus and we don't know enough yet so injecting even a tiny dose into people is a bad idea imo.
The mRNA vaccines are much safer for now.

I don't think you will get a choice. Given a choice seems to have seriously hampered the EUs vaccination programme in Germany and France. Hundreds of thousands of doses of Astra Zeneca go unused in both countries.
Besides we have already used 10s of thousands of AZ on our frontline healthcare workers with a plan to start using it on medically vulnerable adults.

WhiteMemento9

eagle eye wrote: »

I was all AZ for a long time, stupid me.
I'm now against it, it being a traditional style vaccine.
Fact is we are still learning about this virus and we don't know enough yet so injecting even a tiny dose into people is a bad idea imo.
The mRNA vaccines are much safer for now.

You were wrong but now you are right but we don't know enough yet. Thanks, we would be lost without sages like you on this forum.

hmmm

Results from 14 million US vaccinations show no serious adverse events caused by the vaccines:
https://consumer.healthday.com/b-2-19-approved-u-s-covid-vaccines-are-safe-new-review-confirms-2650623525.html

embraer170

ACitizenErased wrote: »

https://twitter.com/UniofOxford/status/1363900139891548166?s=20

Could this be because because the Pfizer has been given to an older population group?

I have googled a bit and I can’t find any reference to the age breakdown of the vaccines administered in the study group.

lukas8888

AdamD wrote: »

Given the results from the UK should we be clearing AZ for use on our over 65s?

Not approving it at first may well have reduced confidence in taking it within that age group

My understanding of AZ was that it was not recommended for over 70s, and
the 65 to 69 age group were getting AZ.
Am i incorrect.

eagle eye

eagle eye wrote: »

I was all AZ for a long time, stupid me.
I'm now against it, it being a traditional style vaccine.
Fact is we are still learning about this virus and we don't know enough yet so injecting even a tiny dose into people is a bad idea imo.
The mRNA vaccines are much safer for now.

Maybe you want to read up on how the vaccine actually works

astrofool

This is the tweet that matters, if they can release the data behind it (and what highly effective means), it may allow us to use AZ on >70 and boost public confidence in AZ:
https://twitter.com/UniofOxford/status/1363900849299353607

Turtwig

astrofool wrote: »

This is the tweet that matters, if they can release the data behind it (and what highly effective means), it may allow us to use AZ on >70 and boost public confidence in AZ:
https://twitter.com/UniofOxford/status/1363900849299353607

NewScientist's report on the story kinddd of touched on that second tweet.

Among people over 80, who are most at risk from covid-19, hospitalisation was reduced by 81 per cent when results from both vaccines were combined. There isn’t enough data yet to separate out the effects of the two different vaccines in this age group.

Read more: https://www.newscientist.com/article/2268769-first-real-world-covid-19-vaccine-studies-show-spectacular-results/#ixzz6nFKsolxl

astrofool

Turtwig wrote: »

NewScientist's report on the story kinddd of touched on that second tweet.

Well that's a bit of a pain.

noplacehere

How will the vulnerable under 65 be registered? Do they get theirs through the GP or pharmacy or?

nocoverart

Turtwig wrote: »

This makes absolutely no sense. Are you saying if you were offered the AZ vaccine you'd refuse it now?

Not sure what you mean by injecting people is a bad either.Anyone taking AZ is a bad idea?

I wouldn’t take any notice, one of the worst posters on here over the last year... along with de frog and the fairy. Some caveat emperor or something like that is an honorable mention too.

JTMan

Interesting FT article on how CureVac "hopes to come out on top" here (paywall).

- German government, GlaxoSmithKline and Bill Gates have invested in CureVac.
- US government / Trump admin allegedly attempted to buy CureVac.
- CureVac’s candidate is able to survive in standard fridge temperatures for at least three months.
- At 12 micrograms per dose, it requires the smallest amount of active ingredient among the mRNA vaccines, enabling more efficient distribution.
- Two weeks ago, CureVac began submitting approval data to the EMA.
- Manufacturing deals with Germany’s Wacker Chemie and Rentschler as well as with France’s Fareva.
- First batch of doses secured by the EU.
- Initial readout from large-scale phase 3 trials is expected in March.

Not clear when CureVac expect EMA approval but the article says "multiple key regulators" are expected to approve by mid year. So I guess EMA approval will be sometime in the April-June timeline.

JTMan

Germany are considering vaccine certificates. Israel already issue "green passports" ...

https://twitter.com/DeItaone/status/1364139580102959104

hmmm

Sanofi to produce 12 million doses a month of the J&J vaccine.
https://www.fiercepharma.com/pharma/after-pfizer-deal-sanofi-offers-a-hand-to-johnson-johnson-for-covid-19-vaccine-production

It's not clear to me whether this is a new 12 million, or support with existing production. I think it's new capacity.

Cork2021

hmmm wrote: »

Sanofi to produce 12 million doses a month of the J&J vaccine.
https://www.fiercepharma.com/pharma/after-pfizer-deal-sanofi-offers-a-hand-to-johnson-johnson-for-covid-19-vaccine-production

It's not clear to me whether this is a new 12 million, or support with existing production. I think it's new capacity.

That’s great news!! So in total we could be looking at an roughly an extra 130,000 from J&J from May on top of the 600,000 already committed for Q2? So if that’s the case we could be looking at 860,000 people done with one shot!! That’s 17.2% of total population done in 3 months

hmmm

Cork2021 wrote: »

That’s great news!! So in total we could be looking at an roughly an extra 130,000 from J&J from May on top of the 600,000 already committed for Q2? So if that’s the case we could be looking at 860,000 people done with one shot!! That’s 17.2% of total population done in 3 months

Q3 unfortunately. But that's not too far away.
https://www.marketscreener.com/quote/stock/SANOFI-4698/news/Sanofi-to-provide-manufacturing-support-to-Johnson-Johnson-for-their-COVID-19-vaccine-to-help-ad-32498642/

Chomper.

The UK must be confident on the vaccines dealing with variants

titan18

JTMan wrote: »

Germany are considering vaccine certificates. Israel already issue "green passports" ...

https://twitter.com/DeItaone/status/1364139580102959104

I'd imagine it will happen but not sure you can do it before you've given the population the chance to be vaccinated, so for us probably can't happen til July or August really.

ceegee

8232 for Saturday