Vaccine Megathread - See OP for threadbans

Rebelbrowser

Flying Fox wrote: »

Good point, I'm not sure if there could be legal implications.

I think AZ, or someone else with standing, would have to take a Judicial Review against NIAC. Would have to show that NIAC either erred procedurally in its decision making (no evidence) or that the decision of NIAC was irrational - which is a high bar. Courts reluctant understandably to supplant their non expert view for the view of an expert group like NIAC. So once NIAC have some reasonable basis for distinguishing between AZ and J&J they'd be fine.

PhilOssophy

All it will take is to get a bunch of "influencers" to post a video of them getting the vaccine and young people will line up I reckon. And by influencers, I mean sports people, musicians, actors, etc rather than wannabe people of importance!
But as the above poster said, I have come across grads in my work and every one of them is happy to get a vaccine. And my nieces/nephews who are that age say the same. Now maybe they are the educated ones - i.e. not gullible enough to be lead by conspiracy theorists, but I think the uptake will be much higher than people suggest.

Eod100

Moderna waiving its IP rights. Good to see

https://investors.modernatx.com/news-releases/news-release-details/statement-moderna-intellectual-property-matters-during-covid-19/

Vicxas

Eod100 wrote: »

Moderna waiving its IP rights. Good to see

https://investors.modernatx.com/news-releases/news-release-details/statement-moderna-intellectual-property-matters-during-covid-19/

We'll be having Tesco value vaccinations in no time!

PhilOssophy

Vicxas wrote: »

We'll be having Tesco value vaccinations in no time!

Imagine the queue outside Lidl on a Thursday when they appear in the specials catalogue.....

Eod100

Eod100 wrote: »

Moderna waiving its IP rights. Good to see

https://investors.modernatx.com/news-releases/news-release-details/statement-moderna-intellectual-property-matters-during-covid-19/

Actually seems to be from October 2020 so may be old news. Just saw it doing the rounds this morning.

Probes

Eod100 wrote: »

Moderna waiving its IP rights. Good to see

https://investors.modernatx.com/news-releases/news-release-details/statement-moderna-intellectual-property-matters-during-covid-19/

They did that a good while ago. Not much has happened so I wonder how specialised it is to make these vaccines, perhaps no one apart from themselves and Pfizer can do it anyway?

namloc1980

odyssey06 wrote: »

A family member is in Group 7 of high risk, under 60.
Their GP surgery is not participating in the rollout because "AZ is not available".

Family member now seems to be in limbo as there doesn't seem to be any Plan B?
GP hasn't said anything along the lines of "We will register you for an MVC" and self registration on HSE is age based only.

Anyone else in same boat?

I am in Group 7 and getting vaccinated at my GP with Pfizer on Thursday. You need to insist on a better answer from the GP as to why they aren't looking after their Group 7 patients.

rm212

It seems like Sanofi have entered an agreement with Moderna to manufacture doses of their COVID-19 vaccine on behalf of Moderna.

titan18

namloc1980 wrote: »

I am in Group 7 and getting vaccinated at my GP with Pfizer on Thursday. You need to insist on a better answer from the GP as to why they aren't looking after their Group 7 patients.

Interesting, might have to contact my GP this week then. I was waiting until next week before doing it as I should be in group 7 but I think you're Cork based like myself so maybe they've moved on to our group now.

ACitizenErased

rm212 wrote: »

It seems like Sanofi have entered an agreement with Moderna to manufacture doses of their COVID-19 vaccine on behalf of Moderna.

CNBC reporting that it's from their New Jersey plant

Red Silurian

MerlinSouthDub wrote: »

If the 82% of adult population target by end of June still applies (and I think it does), then everyone 30+ would get a dose by end of June. Good chart here:

https://twitter.com/RachelLavin/status/1383741192085467141/photo/1

So judging by that chart the plan is

1.5m first doses - we start on the over 55s
2.5m first doses - we start on the over 45s
3m first doses - we start on the over 35s
3.5m first doses - we start on the over 25s
4.2m first doses - we start on the Under 25s

Accurate?

eoinbn

Eod100 wrote: »

Actually seems to be from October 2020 so may be old news. Just saw it doing the rounds this morning.

WHO seem to be full of idiots.
The idea that sharing the IP would allow a huge uptick in production is daft. There is a shortage of raw materials and a shortage of specialist. Moderna are struggling to find people in Switzerland to ramp up production. Novavax, Curevac, SII are all having issues sourcing materials.
Having more manufactures will only make that situation worse.
As we have seen in the US with Emergent BioSolutions it is very easy for things to go wrong. If that had happen it a more corrupt country it could well have been swept under the carpet with potentially catastrophic consequences.

rm212 wrote: »

It seems like Sanofi have entered an agreement with Moderna to manufacture doses of their COVID-19 vaccine on behalf of Moderna.

Seems to be fill and finish. Similar to what they are doing for Pfizer/BioNtech from July.

Tyrone212

[Deleted User] wrote: »

Expected rates of myocarditis are 10-20 per 100k per year. So if you take the lower end of that range Israel would expect about 250 cases in 3 months. Younger males also have a higher rate of myocarditis than the general population. So, 62 cases in Israel with a higher prevalence in younger males is not something to be overly concerned about

Concerning aspect is 56 out 62 cases came just after the second shot. Not many vaccinated in that age group either in comparison to others. Anyway it is being investigated so we'll find out soon enough.

If anything comes of it, along with the AstraZeneca news it will make some young people weary about getting their covid shot like myself and I'm very pro vaccine. In UK analysis the risks outweigh the rewards in under 30s from taking it, if it turns out to be same with Pfizer then I'm not sure what I'd do. I'd still get vaccinated, I'd just wait to see which is safest for my age first.

I'm very pro vaccine BTW I'm just specifically talking about my age group. A bit older and I'd have no concerns.

Russman

Actually, if J&J is approved today (even with some restrictions), does that potentially bring forward our target date of end of June for the 80% first dose ?
I may be mis-remembering, but am I correct in saying that our forecasts don't currently include anything from J&J ? So anything we end up able to use will be a "bonus" of sorts ?

WoollyRedHat

Anyone know what day the NIAC is due to make a decision about J & J on?

Bit cynical

Strazdas wrote: »

But we're gaining pace on them rapidly. In mid March, we were nearly three months behind them. At the moment it's eight weeks.....soon it will be four weeks etc.

This is very true. In term of pace by the end of May we should be vaccinating at roughly the same pace as the UK however at that point we'll still only be were they were at the end of March in terms of total vaccines administered and this is assuming that targets are met.

Tyrone212

Tyrone212 wrote: »

Concerning aspect is 56 out 62 cases came just after the second shot. Not many vaccinated in that age group either in comparison to others. Anyway it is being investigated so we'll find out soon enough.

If anything comes of it, along with the AstraZeneca news it will make some young people weary about getting their covid shot like myself and I'm very pro vaccine. In UK analysis the risks outweigh the rewards in under 30s from taking it, if it turns out to be same with Pfizer then I'm not sure what I'd do. I'd still get vaccinated, I'd just wait to see which is safest for my age first.

I'm very pro vaccine BTW I'm just specifically talking about my age group. A bit older and I'd have no concerns.

however, this number rose to 1-in-20,000 among those aged 16-30.

Lower than the expected rate

RavenBea17b

EU to sue AstraZeneca, announced just now. Late delivery etc

Corholio

RavenBea17b wrote: »

EU to sue AstraZeneca, announced just now. Late delivery etc

Donnelly smirking like a Cheshire cat that he leaked it ahead of time, that'll get him some more mentions, he can give himself a gold star now.

Turtwig

Tyrone212 wrote: »

In UK analysis the risks outweigh the rewards in under 30s from taking it

This isn't technically correct. The risks for under 30s only outweigh the rewards when the daily incidence rate of covid was 2 per 10,000 or lower. For incidences of 6 per 10,000 or higher the vaccine benefits significantly outweighed the risks.

Their assessment also did not take into account underlying health conditions that increase the risk of a poor outcome for individuals.

Tyrone212

Turtwig wrote: »

This isn't technically correct. The risks for under 30s only outweigh the rewards when the daily incidence rate of covid was 2 per 10,000 or lower. For incidences of 6 per 10,000 or higher the vaccine significantly outweighed the risks.

They also did not take into account underlying health conditions that increase the risk of a poor outcome for individuals when making their assessment.

Yes you're correct however they had logged 4 cases per 1m when they released that and last Thursday they upped to it to 7.9m. So it remains to be seen I guess.

Turtwig

Tyrone212 wrote: »

Yes you're correct however they had logged 4 cases per 1m when they released that and last Thursday they upped to it to 7.9m. So it remains to be seen I guess.

Yeah I forgot that actually. Fair point. The identified incidence rate of CVST has increased to about in 1 in 125,000? (might even be a newer figure) It'll be interesting to see how that affects their updated analysis.

Christy42

PhilOssophy wrote: »

All it will take is to get a bunch of "influencers" to post a video of them getting the vaccine and young people will line up I reckon. And by influencers, I mean sports people, musicians, actors, etc rather than wannabe people of importance!
But as the above poster said, I have come across grads in my work and every one of them is happy to get a vaccine. And my nieces/nephews who are that age say the same. Now maybe they are the educated ones - i.e. not gullible enough to be lead by conspiracy theorists, but I think the uptake will be much higher than people suggest.

Having people publicly get the vaccine is a big deal. It is why it is a good thing to have them post about it when done or to show it being done.

Elvis being credited with helping the public perception with the polio vaccine getting it done in front of the media. Hopefully it will end up with a high rate of getting it done.

Redo91

Russman wrote: »

Actually, if J&J is approved today (even with some restrictions), does that potentially bring forward our target date of end of June for the 80% first dose ?
I may be mis-remembering, but am I correct in saying that our forecasts don't currently include anything from J&J ? So anything we end up able to use will be a "bonus" of sorts ?

I was wondering this too. Surely would make a big difference.

hmmm

Christy42 wrote: »

Having people publicly get the vaccine is a big deal. It is why it is a good thing to have them post about it when done or to show it being done.

The surveys aren't really showing much in the way of hesitancy in younger people - I think apathy will be a bigger issue. Perhaps it's going to be less about convincing them to take it, and more about making it convenient - could we get some sort of mobile clinics for example?

Asking a 20 year old to take a trek out to a vaccination centre sounds like a good way for it not to happen.

PhilOssophy

hmmm wrote: »

Asking a 20 year old to take a trek out to a vaccination centre sounds like a good way for it not to happen.

What do you want - vaccinators to drive to their house?

SleetAndSnow

hmmm wrote: »

Asking a 20 year old to take a trek out to a vaccination centre sounds like a good way for it not to happen.

As a 20 year old that is in College, and has friends in multiple different types of courses, it'll be grand . Everybody I have talked too so far just 'wants that needle jabbed into my arm'

astrofool

They'll have them on the college campus if they need to (like they do for flu vaccinations).

ACitizenErased

SleetAndSnow wrote: »

As a 20 year old that is in College, and has friends in multiple different types of courses, it'll be grand . Everybody I have talked too so far just 'wants that needle jabbed into my arm'

I haven't seen any hesitancy either across multiple courses