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Vaccine Megathread No 2 - Read OP before posting

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  • Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Amazing data on John Campbell's video today

    Percentage of people testing positive in:

    • England - 0.09%
    • Wales - 0.02%
    • Northern Ireland - 0.06%
    • Scotland - 0.05%


    Ireland is surely on the trajectory for similar numbers soon as the Vaccinations ramp up

    Before the HSE hack Ireland's positivity rate was at 2.7%









  • Registered Users, Registered Users 2 Posts: 5,848 ✭✭✭podgeandrodge


    ShineOn7 wrote: »
    Amazing data on John Campbell's video today

    Percentage of people testing positive in:

    • England - 0.09%
    • Wales - 0.02%
    • Northern Ireland - 0.06%
    • Scotland - 0.05%


    Ireland is surely on the trajectory for similar numbers soon

    Before the HSE hack Ireland's positivity rate was at 2.7%








    And stopping anyone having a pint after 11.30pm will surely make a massive difference too.


  • Registered Users, Registered Users 2 Posts: 11,205 ✭✭✭✭hmmm


    If this proves correct it will be wonderful news. Lifetime protection, no boosters required.

    https://twitter.com/apoorva_nyc/status/1397604467906859011?s=21


  • Registered Users Posts: 733 ✭✭✭PmMeUrDogs


    That's it, eat as much as possible, smoke as much as possible, drink as much as possible.

    Basically don't give a hoop about how healthy you are and then expect a 'priority' to get a vaccine because you are a fat feck.

    Great system that is.

    utter bs

    It's really, really basic.

    We don't refuse medical treatment on the grounds of poor life choices.

    Those who are statistically more likely to die from covid, get the vaccine first.

    If you're fit and healthy, you're not likely to die, so you're less at risk.


    If we vaccinated all the young and healthy first, we'd still be in complete lockdown as all the unhealthy people fill up the hospitals.


    Vaccinating the medically vulnerable first is what's getting us out of lockdown.


  • Registered Users Posts: 5,883 ✭✭✭Wolf359f


    ShineOn7 wrote: »
    Amazing data on John Campbell's video today

    Percentage of people testing positive in:

    • England - 0.09%
    • Wales - 0.02%
    • Northern Ireland - 0.06%
    • Scotland - 0.05%


    Ireland is surely on the trajectory for similar numbers soon as the Vaccinations ramp up

    Before the HSE hack Ireland's positivity rate was at 2.7%








    Ireland's positivity rate is based on PCR tests.
    Not sure where he's getting those positivity rates from.


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  • Registered Users, Registered Users 2 Posts: 8,748 ✭✭✭degsie


    So, we will have 40 yo's fully vaccinated with Pfizer well before 60 yo's with Astrazeneca due to the 12 week wait. How is this making any sense?


  • Registered Users, Registered Users 2 Posts: 14,065 ✭✭✭✭Goldengirl


    revelman wrote: »
    Well, to play Devil’s advocate, some are theorising that there is also a tiny possibility of myocarditis as a potential side effect of Pfizer, especially in males (though these tend to be under 40)

    The CDC is once again investigating this: https://www.theguardian.com/world/2021/may/23/cdc-studying-reports-of-heart-inflammation-in-young-covid-vaccine-recipients

    The initial assessment was that rates of myocarditis post-vaccination are no different to background rates normally seen in the population. But myocarditis is generally caused by viral infection and there are far fewer “normal” viruses circulating. So there is a theoretical possibility of a link with the MRNA vaccines.

    Risk is men under 30 afaik.


  • Registered Users Posts: 5,883 ✭✭✭Wolf359f


    degsie wrote: »
    So, we will have 40 yo's fully vaccinated with Pfizer well before 60 yo's with Astrazeneca due to the 12 week wait. How is this making any sense?

    If they decided not to use AZ, then the 60-69 group would have gotten all Pfizer and the 50 yo's would be waiting weeks and weeks for their first jab, and then the 40 yo's would be waiting weeks and weeks more etc...


  • Registered Users, Registered Users 2 Posts: 7,808 ✭✭✭Fann Linn


    degsie wrote: »
    So, we will have 40 yo's fully vaccinated with Pfizer well before 60 yo's with Astrazeneca due to the 12 week wait. How is this making any sense?

    Luck of the draw I think. I got Pfizer last Saturday, a week earlier at the same time in the same centre a workmate got AZ.


  • Registered Users Posts: 1,570 ✭✭✭Tyrone212


    Wolf359f wrote: »
    Ireland's positivity rate is based on PCR tests.
    Not sure where he's getting those positivity rates from.

    He's a goon.


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  • Registered Users, Registered Users 2 Posts: 8,748 ✭✭✭degsie


    Wolf359f wrote: »
    If they decided not to use AZ, then the 60-69 group would have gotten all Pfizer and the 50 yo's would be waiting weeks and weeks for their first jab, and then the 40 yo's would be waiting weeks and weeks more etc...

    Fair enough but the current variants of concern are more harmful to the older age brackets.


  • Registered Users, Registered Users 2 Posts: 5,831 ✭✭✭Charles Babbage


    ShineOn7 wrote: »
    Amazing data on John Campbell's video today

    Percentage of people testing positive in:

    • England - 0.09%
    • Wales - 0.02%
    • Northern Ireland - 0.06%
    • Scotland - 0.05%


    I suspect these include non PCR tests so the rates are not strictly comparable.

    The NI dashboard shows 1.14% positivity last week which is not bad as it was around 2% the previous week.

    But the direction is clear and vaccination is the way forward.


  • Registered Users Posts: 5,883 ✭✭✭Wolf359f


    degsie wrote: »
    Fair enough but the current variants of concern are more harmful to the older age brackets.

    Yeah blame NIAC for not having a time machine.


  • Registered Users Posts: 5,883 ✭✭✭Wolf359f


    I suspect these include non PCR tests so the rates are not strictly comparable.

    The NI dashboard shows 1.14% positivity last week which is not bad as it was around 2% the previous week.

    But the direction is clear and vaccination is the way forward.

    Oh I know the direction is clear, just wondering did he forget to multiply by 100 for the %


  • Registered Users, Registered Users 2 Posts: 14,065 ✭✭✭✭Goldengirl


    hmmm wrote: »
    If this proves correct it will be wonderful news. Lifetime protection, no boosters required.

    https://twitter.com/apoorva_nyc/status/1397604467906859011?s=21

    Caveat ..No proof on variants .


  • Registered Users, Registered Users 2 Posts: 2,922 ✭✭✭dominatinMC


    Goldengirl wrote: »
    Caveat ..No proof on variants .

    Yet.


  • Registered Users, Registered Users 2 Posts: 3,876 ✭✭✭Polar101


    Leo Varadkar is saying 40-45 olds can register "in the coming days" and opt-in for J&J. I assume he means 40-44, because 45's can already register. But 45-49's didn't get an option like that - are they out of the J&J rollout then?


  • Posts: 0 [Deleted User]


    Goldengirl wrote: »
    Caveat ..No proof on variants .

    Proof exists in mathematics, not medicine.


  • Registered Users, Registered Users 2 Posts: 14,051 ✭✭✭✭josip


    Wales has over half thec18 to 29 group done with one dose


    What ages are getting their 2nd doses over there, are they into the 40s?


  • Posts: 0 [Deleted User]


    Goldengirl wrote: »
    Caveat ..No proof on variants .

    No evidence whatsoever on vaccine evasion from any variant once fully vaccinated


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  • Registered Users Posts: 2,251 ✭✭✭speckle


    hmmm wrote: »
    If this proves correct it will be wonderful news. Lifetime protection, no boosters required.

    https://twitter.com/apoorva_nyc/status/1397604467906859011?s=21

    Excellant news...also puts people with a good response to the wild/natural infection in a good place also...if not mistaken we have had aprox 10,000 vaccine breakthru cases in US and 50 natural confirmed infections( definetly might be some unaccounted for)...certainly they should not be treated differently as second class citizens when opening up and should be first in the queue for t cell tests if required...

    This is not saying at all to run out and get a natural covid infection and as with the caveat already mentioned above..they would also be placed just as good as those with vaccines if a new variant arrived.

    We saw this possibility already from the 'forest' plots from research papers already posted on this thread from hmmiz...their antibody response was rapidly there better than the no infection ever group when challenged by just the spike protein.

    Would be great news and potentially peace of mind also for the tiny minority who either cannot be vaxd due to previous serious adverse events or severe allergys to components or those who could only receive shot one but not two because of the above also ...who have had a previous infection.

    Remember though the possiblity of a minority eg those immunospressed via meds etc may not have mounted a good antibody response or those who needed plasma first time around but they were in the early cohorts.

    Hmmm you have made my day from crap to sooo good I could kiss you..metaphorically :D


  • Moderators, Home & Garden Moderators, Recreation & Hobbies Moderators Posts: 7,698 Mod ✭✭✭✭delly


    Well to put that in context, a good friend got the old school covid in November, then got reinfected with the UK variant in March. Give or take it was 5 months between infections, no not sure if I trust natural immunity to variants is as good as the vaccine. Granted that case could be the exception, but it certainly surprised me.


  • Posts: 0 [Deleted User]


    delly wrote: »
    Well to put that in context, a good friend got the old school covid in November, then got reinfected with the UK variant in March. Give or take it was 5 months between infections, no not sure if I trust natural immunity to variants is as good as the vaccine. Granted that case could be the exception, but it certainly surprised me.

    That was happening before the UK variant.


  • Registered Users, Registered Users 2 Posts: 3,074 ✭✭✭questionmark?


    eoinbn wrote: »
    It's 300k and that includes GPs.

    It was stated earlier this week that they didn't have all the GP figures due to the ongoing hacking situation. Was there a statement saying that GP figures are now included?


  • Registered Users, Registered Users 2 Posts: 14,065 ✭✭✭✭Goldengirl


    No evidence whatsoever on vaccine evasion from any variant once fully vaccinated

    That is not what this is about .
    That Twitter thread talking about memory BCells providing lifetime immunity once recovered from Covid infection .
    This has not been shown but " may " happen as these bone marrow cells provide lasting immunity and produce antibodies to the infection.
    However this would be shown to be from the strain infected with , but no proof whatsoever that it will provide lasting immunity to variants .
    Nobody is talking about vaccine evasion, I am saying the opposite .
    Boosters tweaked for variants will most likely be needed.


  • Registered Users Posts: 2,251 ✭✭✭speckle


    delly wrote: »
    Well to put that in context, a good friend got the old school covid in November, then got reinfected with the UK variant in March. Give or take it was 5 months between infections, no not sure if I trust natural immunity to variants is as good as the vaccine. Granted that case could be the exception, but it certainly surprised me.

    Were they pcr'd each timesnd how many cycles and sequenced at least the second time...as they were trying to sequence 2nd infections as they were rare to see the varient? Symptoms each time worse/better/none and contact traced to a previous case? Did they have an antibody test after the first infection? Any immunsuppressant or other co morbidties like I mentioned? Always interested in 2nd infections as they are rare..many turn out to be false postives either first or second infection. Find this topic area of covid scientifically fascinating. And it is equally important to then see how they respond if vacinated...more of those forest plots please.
    Edit...and it goes without saying I hope your friend recovered well.


  • Registered Users, Registered Users 2 Posts: 28,280 ✭✭✭✭drunkmonkey


    speckle wrote: »

    they would also be placed just as good as those with vaccines if a new variant arrived.

    That's not what the study said, it's good news for people who caught covid and had a mild infection it didn't study the vaccinated.

    Months after recovering from mild cases of COVID-19, people still have immune cells in their body pumping out antibodies against the virus that causes COVID-19, according to a study from researchers at Washington University School of Medicine in St. Louis. Such cells could persist for a lifetime, churning out antibodies all the while.
    https://medicine.wustl.edu/news/good-news-mild-covid-19-induces-lasting-antibody-protection/


  • Posts: 0 [Deleted User]


    Goldengirl wrote: »
    That is not what this is about .
    That Twitter thread talking about memory BCells providing lifetime immunity once recovered from Covid infection .
    This has not been shown but " may " happen as these bone marrow cells provide lasting immunity and produce antibodies to the infection.
    However this would be shown to be from the strain infected with , but no proof whatsoever that it will provide lasting immunity to variants .
    Nobody is talking about vaccine evasion, I am saying the opposite .
    Boosters tweaked for variants will most likely be needed.

    Will try and dig out the article I read on this. Basically because of the nature of how Covid infects, for a variant to repeatedly and consistently bypass vaccine immunity, for the mrna and possibly viral vector vaccines at least, it would somehow need to completely reinvent how it infects. Natural immunity is more random in the specific response that is triggered. That’s why some small changes can bypass. The vaccine is specific immunity to the spike protein. As long as there is the spike protein, immune response will pick it up. For a mutation significant enough to alter the spike protein to bypass immunity it would need to first become a less infectious virus with associated competitive loss. Older type vaccines, such as for the flu, don’t code for the spike protein specifically which is why they are bypassed more easily. Also see sinovav


  • Registered Users Posts: 523 ✭✭✭Mark1916




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  • Registered Users, Registered Users 2 Posts: 28,280 ✭✭✭✭drunkmonkey


    Goldengirl wrote: »
    However this would be shown to be from the strain infected with , but no proof whatsoever that it will provide lasting immunity to variants .

    There must be some evidence, the beauty of the french vaccine is that it uses the whole virus not just the spike protein which is said to protect against the variants, people who are naturally infected should also have the same benefits.


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