Vaccine Megathread No 2 - Read OP before posting

How long should I wait between the two doses for a teen?

Minimum is 21 days I know, but I had 5 weeks + 2 day between my Pfizer doses and my wife had 4 weeks + 2 days.

At the time there seemed to be evidence that a longer wait is better - is that still the case or I should proceed with 2nd dose after 3 weeks?

Interesting to see correlations from US.

Vaccination Percentage and Seven-Day Case Rates

Vaccination Percentages and Hospital Admissions/100K

Vaccination Percentages and Deaths/100K

Source: https://insights.som.yale.edu/insights/soaring-covid-rates-in-the-south-show-why-we-need-vaccine-mandates

Since Connecticut seems to be doing really well with vaccines and low cases, and is close to our own stats, I dug out a recent state-level COVID-19 report (from Sept 8/9).

There's some really interesting stats and charts in there detailing relative risks for vaxxed/unvaxxed. If only we had this quality of reporting in Ireland!

This chart is not risk-adjusted (e.g. for age), and as at-risk people are more likely to be vaccinated (data here for CT) I think the individual risk reduction must be much greater than 5x.

Hi All, wonder can anyone help? My son has been deemed a close contact from outside in the yard at school. He is 13 and "in contact in the yard for break WITH his mask on" on thursday . He has had BOTH vaccines doses but only since Tuesday. The HSE have booked him for test tomorrow Monday. Should he be ok to return to school on Wednesday if test is negative since by then he will be FULLY vaccinated (assuming still no symptoms).

So to recap

Tuesday 2nd dose of vaccine

Thursday contact with since confirmed positive case..outside in yard with mask.

Sunday negative antigen test

Monday HSE test (Assuming it be negative...)

Wednesday can he return to school?

HSE very vague on it and said up to yourself...I said surely ok by Wednesday to return...

thoughts?

thanks

What's the story with booster shots? Is Ireland going for a third booster shot?

@TheMammy wrote

I would daily antigen test until the PCR comes through, and in the mean time send him in unless he's symptomatic.

There's dedicated thread on schools btw.

It depends on the demographic and what you mean by "enough protection". Non-vulnerable 40+ year olds vaccinated 6+ months ago by AZ likely have no protection with regard to hospitalisation:

Vaccine effectiveness and duration of protection (khub.net)

As you can see from Table 2, effectiveness against hospitalisation decreases with time

All people beyond 20 weeks are averaged together, hence, because effectiveness decreases with time, there's a massive confidence interval for the 20+ week averages. If you were to break it down into more discrete buckets you'd continue to see decreased effectiveness with each successive time period. 29.7% (the lower bound of the confidence interval you posted) is no protection, 14.1% for 65+ year olds is no protection, and so on.

That's not what they're saying.

The full quote is "there was limited data in the 40 to 64 years group for this period and confidence intervals overlapped", and by this they mean that there may not be a statistically significant difference between the 20+ week and the previous time period. They aren't saying that the confidence intervals are large because of a lack of data. 2 million 40-64 year olds are included in this analysis.

I'm not picking the lower bound, I'm saying that effectiveness lies somewhere in this range with 95% confidence, and as shown by this analysis, decreases with time. If it's 10-30% within any amount of weeks, let alone 20, then that's ineffective.

I doubt we will be doing this tbh .

Certainly not before other countries have caught up .

Again, you're banging on trying to misuse data in a paper, here is the table for all to see:

And again, this is the conclusion the experts who wrote the paper reached:

"Our study provides evidence of significant waning against symptomatic disease but limited waning against severe disease over a period of at least 5 after administration of second doses in a programme with an extended interval between first and second doses. Waning appeared to be greater in older age groups and among individuals in clinical risk groups, suggesting that these individuals should be prioritised for booster doses"

You're doing a fair amount of reaching and being disingenuous with this one, will be interesting to see where you go from here.

And again, as I've asked before, do you believe the vaccines are effective and that everybody should take one? And a new one for you: If you believe what you're writing, what do you suggest should be done instead? Back to full lockdown?

The topic is vaccines, you've posted a paper showing how well they work and are trying to pass it off as vaccine failure for whatever reason, as you've tried to do before, before running away.

Anyway:

And again, as I've asked before, do you believe the vaccines are effective and that everybody should take one? And a new one for you: If you believe what you're writing, what do you suggest should be done instead? Back to full lockdown?

You said this

The data in the paper does not support this, you cover yourself by using the word "likely". But let's take it as true, what are the next steps? Do you recommend boosters for everyone over 40 every 6 months?

So it’s ok to subject children to a vaccine that offers them more risk than benefit statistically? And this is for the benefit of whom as all adults eligible who are going to get the vaccine have it.

Children are more at risk from flu, norovirus and even RSV than they are from Covid. Statistically children are more likely to be struck by lightning than die from Covid. Vaccines do not stop transmission. What exactly is the benefit of forcing this relatively new vaccine on young children? This trial data is also over an extremely short time period relatively speaking to other childhood inoculations. These drug companies should be distributing their vaccines to the many areas of the world who still need them rather than trying to line their pockets pushing them on younger children who don’t.

Both unvaccinated and vaccinated people in hospitals are almost entirely those that can be considered vulnerable, i.e. Multiple comorbidities, history of respiratory illness etc. Therefore they should have been vaccinated, ideally. Hospital capacity is separate important issue.